| 1 | Department of Health and Human Services | $2.0T | $9.5T | 38.3% | 15 |
| 2 | Social Security Administration | $1.6T | $7.4T | 29.8% | — |
| 3 | Department of Defense | $502B | $2.2T | 9% | 25 |
| 4 | Department of Veterans Affairs | $288B | $1.4T | 5.6% | 3 |
| 5 | Department of Agriculture | $187B | $966B | 3.9% | 21 |
| 6 | Department of Transportation | $134B | $623B | 2.5% | 10 |
| 7 | Department of Education | $96B | $457B | 1.8% | — |
| 8 | Department of Homeland Security | $73B | $361B | 1.5% | 13 |
| 9 | Department of Housing and Urban Development | $78B | $344B | 1.4% | 7 |
| 10 | Department of Energy | $80B | $300B | 1.2% | 1 |
| 11 | General Services Administration | $24B | $122B | 0.5% | 3 |
| 12 | Agency for International Development | $12B | $118B | 0.5% | — |
| 13 | Department of State | $14B | $106B | 0.4% | 1 |
| 14 | Environmental Protection Agency | $27B | $106B | 0.4% | — |
| 15 | Department of Commerce | $25B | $88B | 0.4% | 8 |
| 16 | Department of the Interior | $19B | $85B | 0.3% | 11 |
| 17 | National Aeronautics and Space Administration | $17B | $84B | 0.3% | — |
| 18 | Pension Benefit Guaranty Corporation | $6.6B | $80B | 0.3% | — |
| 19 | Department of the Treasury | $9.0B | $69B | 0.3% | 9 |
| 20 | Railroad Retirement Board | $15B | $68B | 0.3% | — |
| 21 | Department of Justice | $11B | $67B | 0.3% | 8 |
| 22 | Federal Communications Commission | $6.3B | $66B | 0.3% | — |
| 23 | Department of Labor | $11B | $51B | 0.2% | 7 |
| 24 | National Science Foundation | $8.9B | $42B | 0.2% | — |
| 25 | Small Business Administration | $996M | $23B | 0.1% | — |
| 26 | Corporation for National and Community Service | $700M | $4.0B | 0% | — |
| 27 | Millennium Challenge Corporation | $291M | $2.9B | 0% | — |
| 28 | Securities and Exchange Commission | $498M | $2.9B | 0% | — |
| 29 | U.S. International Development Finance Corporation | −$1.7B | $2.3B | 0% | — |
| 30 | U.S. Agency for Global Media | $376M | $2.2B | 0% | — |
| 31 | Office of Personnel Management | $199M | $1.8B | 0% | — |
| 32 | Executive Office of the President | $351M | $1.5B | 0% | 1 |
| 33 | Institute of Museum and Library Services | $258M | $1.4B | 0% | — |
| 34 | National Archives and Records Administration | $209M | $1.2B | 0% | 1 |
| 35 | Appalachian Regional Commission | $270M | $1.0B | 0% | — |
| 36 | Nuclear Regulatory Commission | $185M | $976M | 0% | — |
| 37 | Gulf Coast Ecosystem Restoration Council | $175M | $775M | 0% | — |
| 38 | National Endowment for the Humanities | $73M | $765M | 0% | — |
| 39 | National Endowment for the Arts | $120M | $713M | 0% | — |
| 40 | Consumer Financial Protection Bureau | $116M | $619M | 0% | — |
| 41 | Government Accountability Office | $117M | $584M | 0% | 1 |
| 42 | Peace Corps | $69M | $560M | 0% | — |
| 43 | Federal Trade Commission | $93M | $499M | 0% | — |
| 44 | Commodity Futures Trading Commission | $68M | $407M | 0% | — |
| 45 | Denali Commission | $178M | $355M | 0% | — |
| 46 | District of Columbia Courts | $63M | $312M | 0% | — |
| 47 | Equal Employment Opportunity Commission | $49M | $270M | 0% | — |
| 48 | Delta Regional Authority | $73M | $252M | 0% | — |
| 49 | Election Assistance Commission | $13M | $221M | 0% | — |
| 50 | Consumer Product Safety Commission | $32M | $215M | 0% | — |
| 51 | Court Services and Offender Supervision Agency | $37M | $197M | 0% | — |
| 52 | National Labor Relations Board | $27M | $134M | 0% | — |
| 53 | National Transportation Safety Board | $30M | $95M | 0% | — |
| 54 | United States Trade and Development Agency | $15M | $90M | 0% | — |
| 55 | Inter-American Foundation | $0 | $84M | 0% | — |
| 56 | International Trade Commission | $18M | $72M | 0% | — |
| 57 | Federal Election Commission | $14M | $71M | 0% | — |
| 58 | Defense Nuclear Facilities Safety Board | $5.9M | $33M | 0% | — |
| 59 | Federal Maritime Commission | $5.1M | $26M | 0% | — |
| 60 | Selective Service System | $7.4M | $26M | 0% | — |
| 61 | Federal Mediation and Conciliation Service | $1.5M | $24M | 0% | — |
| 62 | Council of the Inspectors General on Integrity and Efficiency | $4.6M | $23M | 0% | — |
| 63 | Merit Systems Protection Board | $3.2M | $22M | 0% | — |
| 64 | John F. Kennedy Center for the Performing Arts | $0 | $15M | 0% | — |
| 65 | Committee for Purchase from People Who Are Blind or Severely Disabled | $2.1M | $13M | 0% | — |
| 66 | National Credit Union Administration | $439K | $11M | 0% | — |